Another important surface antigen is called Rh. Two major antigens or surface identifiers on human RBCs are the A and B antigens. Along with HLA testing, ABO blood typing is used to identify and match organ and tissue transplant donors with recipients who have the same or an acceptable number of matching HLA antigens.īlood types are based on the markers (specific carbohydrates or proteins) or antigens on the surface of red blood cells (RBCs). These antigens vary from person to person and are known as human leukocyte antigens ( HLA). In addition to blood typing, there is another system of proteins (antigens) found on most cells of your body (but not usually red blood cells) that play an important part in responding to foreign substances. Determine the blood group type of potential donors and recipients of organs, tissues, or bone marrow, as part of a workup for a transplant procedure.Units of blood collected from donors are blood typed and then appropriately labeled for use by people that require a specific ABO group and Rh type. Determine the blood group of potential blood donors at a collection facility.These antibodies can cross the placenta and destroy the baby’s red blood cells, resulting in hemolytic disease of the fetus and newborn (HDFN). Because Rh is an antigen, it can elicit an immune response and you could develop antibodies against the Rh antigen. If you are Rh-negative but the father is Rh-positive, the fetus may be positive for the Rh antigen. Rh typing is especially important if you are pregnant because you and your fetus could be incompatible. Determine compatibility between a pregnant woman and her developing baby (fetus).In addition to ABO/Rh typing, other tests such as a red blood cell ( RBC) antibody screen and a crossmatch are performed to determine what type of blood or blood components you can safely receive. While ABO and Rh are the most important, there are many other blood group systems that have to be considered. Ensure ABO and Rh compatibility between your blood type if you require a transfusion of blood or blood components and the unit of blood that will be transfused.Order Test About the Test Purpose of the test
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